I can’t speak to this beyond noting that the two designs which I printed, Clamp Steps and a plate almost full of replacement Essential Clamps (according to the slicer it was $1.67 in filament to print them) were printed in PLA (all I’ve been printing in thus far pending my setting up an exhaust fan) at 100% infill.
There was one discussion on filament which at the end linked to an excellent page going over design ostensibly, but which also subsumes part orientation which is a notable consideration when printing parts which need strength (e.g., the clamps and clamp steps):
but it’s worth reading that entire thread and that entire linked page.