For now I followed @Able’s advice and went for 2 passes (300mm/min, 80% power, but to be honest I did not take the time yet to test various settings and slice the material to see how deep 1 pass goes, at various speed and power values)
What I did confirm is that after an hour of cutting, and despite the constant air evacuation, there is a lingering burnt smell around my machine. Not very strong, but it’s there. I may try and work on an actual smoke shoe. Or rework the supporting bed downdraft-style like @DiscoJon did.